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What is Prolia®?

Prolia® is a prescription medicine used to treat symptoms of osteoporosis and to Increase Bone Mass In Patients receiving certain types of cancer. Prolia® may be used alone or with other medications. Prolia® belongs to a class of drugs called Antineoplastics, Monoclonal Antibody; Monoclonal Antibodies, Endocrine. It is not known if Prolia® is safe and effective in children younger than 4 years of age.  Prolia® is a sterile, preservative-free, clear, Colorless To Pale Yellow Solution. Each 1 mL single-use prefilled syringe of Prolia® contains 60 mg denosumab (60 mg/mL solution), 4.7% sorbitol, 17 mM acetate, 0.01% polysorbate 20, Water for Injection (USP), and sodium hydroxide to a pH of 5.2.

How should Prolia® be Used?

Prolia® comes as a solution (liquid) to be injected subcutaneously (under the skin) in your upper arm, upper thigh, or stomach area. It is usually injected by a doctor or nurse in a medical office or clinic. Prolia® is usually given once every 6 months. Prolia® is used to reduce the risk of Fractures From Multiple Myeloma, or cancer that has spread to the bones, it is usually given once every 4 weeks. Prolia® is used to treat giant cell tumors of bone or high calcium levels caused by cancer, it is usually given every 7 days for the first three doses (on day 1, day 8, and day 15) and then once every 4 weeks starting 2 weeks after the first three doses.

How Prolia® Injection Works?

Prolia® decreases bone resorption (the process by which osteoclasts break the tissue in bones and release minerals, calcium into the blood) by Inhibiting Osteoclast Formation and function and increasing bone mass and strength.

What Should Be Considered Before Taking Prolia®?

Before beginning treatment with Prolia®, ask your doctor about the Benefits And Risks of Prolia®. Talk with them about your health and any concerns you have about Prolia® and its effects. You should also ask your doctor in St. Clair, MI  if Prolia® is safe for you if you have or have had:

• A History Of Thyroid Disease
• Kidney Disease
• Jaw Problems
• Low Calcium Level
• Trouble Absorbing Minerals
• Weakened Immune System Activity
• Additionally, Let Your Doctor Know If You’re Pregnant Or Breastfeeding.

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Side Effects of Prolia®

Common side effects of Prolia® include but are not limited to:

• New Or Unusual Pain In Your Thigh, Hip, Or Groin
• Severe Pain In Joints, Muscles, Or Bones
• Oozing Or Crusting
• Numbness Or Tingly Feeling Around Your Mouth, Fingers Or Toes
• Muscle Tightness Or Contractions
• Overactive Reflexes
• Fever
• Chills
• Night Sweats
• Swelling
• Pain
• Tenderness
• Warmth
• Pain Or Burning When You Urinate
• Increased Or Urgent Need To Urinate

Cautions To Take Prolia®

Do not take Prolia® if you have Low Blood Calcium. Do not take Prolia® if you are pregnant. Do not take Prolia® if you are a nursing mother. Do not take Prolia® if you are allergic to demonstrate or any ingredients in Prolia®. Do not take Prolia® if you receive xgeva.